The group is investigating the (patho-)physiological roles of neuronal non-coding RNAs.Chronic metabolic and neurodegenerative syndromes, such as diabetes mellitus, obesity or Parkinson’s disease, represent a growing epidemic, especially in the constantly aging western populations. These currently incurable complex traits result from a failure in the interplay of environmental factors, humoral signals, extra- and intracellular enzymatic cascades, genetic and epigenetic signals in the central nervous system and in the periphery. Physiological and pathophysiological mechanisms involved in these processes require intensive research to provide the patients with novel therapeutic strategies. The lab has a strong interest in studying the role of distinct neuronal population-specific non-coding RNAs in chronic complex traits disorders.
Requirements: Proficiency in oral and written English, expertise in one or several of the following methods: immunoprecipitation, ChIP-Seq, RNA-Seq, real-timePCR, cloning, western blot, cell culture, behavior and surgery techniques on rodents, vibratome-/microtome-/cryosectioning, microscopy, image processing and analysis, high throughput data analysis, programming.